Short QT Syndrome Patients

Short QT Syndrome – Review articles

Short QT Interval: ECG Phenomenon and Clinical Syndrome Gussak I, Antzelevitch C, Goodman D, Bjerregaard P.. In: Gussak I, Antzelevitch C, Hammill SC, Shen W-K, Bjerregaard P, editors: Cardiac Repolarization – Bridging Basic and Clinical Science. 2003;497-505

Congenital short QT Syndrome A description of current perspective of a short QT interval followed by a description of possible electrophysiological mechanisms and the arrhythmogenic potential. Antzelevitch C, Francis J.. Indian Pacing and Electrophysiology Journal 2004;4(2):46-49.

Editorial with a brief description of the genetic background and channelopathies, which may lead to a short QT interval.

The authors found it noteworthy that substitution of aspartic acid (negative) for asparagine (neutral) in the same position of HERG (N588D) has been linked to the LQT2 syndrome secondary to a loss of function of IKr . This substitution leads to replacement of a neutral amino acid with a negatively charged one, whereas the N588K mutation responsible for some cases of short QT syndrome, secondary to gain of function of IKr , replaces a neutral amino acid(asparagine) with a positively charged one (lysine).

Short QT Syndrome: mechanisms, diagnosis and treatment. Bjerregaard P, Gussak I. Nat Clin Pract Cardiovasc Med. 2005;2:84-87

Clinical characteristics and treatment of short QT syndrome. Wolpert C, Schimpf R, Veltman C, Giustetto C, Gaita F, Borggrefe M. (University Hospital Mannheim, Mannheim, Germany) Expert Rev. Cardiovasc. Ther. 2005;3(4):1-7

Short QT Syndrome Bjerregaard P, Gussak I.. A.N.E. 2005;10(4):436-440

Short QT syndrome. Genotype-phenotype correlations. Borggrefe M, Wolpert C, Antzelevitch C, Veltmann C, Giustetto C, Gaita F, Schimpf R. (University Hospital Mannheim, GermanyJ Electrocardiol 2005;38:75-80

Clinical and molecular genetics of the short QT syndrome Schimpf R, Borggrefe M, Wolpert C. (University Hospital, Mannheim, Germany). Curr Opin Cardiol 2008;23:192-198

Short QT syndrome. Update on a recent entity Maury P, Extramiana F, Sbragia P, Giustetto C, Schimpf R, Duparc A, Wolpert C, Denjoy I, Delay M, Borggrefe M, Gaita F. Archives of Cardiovascilar Disease 2008;101:779-786

Short QT Syndrome: From Bench to Bedside. Patel C, Yan G-X, Antzelevitch C. Circ Arrhythm Electrophysiol 2010;3(4):401-408

Kort QT-syndrom som arvelig sygdom .Møller DV, Hedley PL, Olesen M, Kanters J, Svendsen JH, Christiansen M. Ugeskr Læger 2011;173/6:420-42

Short QT syndrome – Review of Diagnosis and Treatment. Boris Rudic, Rainer Schimpf, Martin Borggrefe. Arrhythm Electrophysiol Rev 2014;3(2):76-79

Recent Advances in Short QT Syndrome Oscar Campuzano, Georgia Sarquella-Brugada, Sergi Cesar, Elena Arbelo, Josep Brugada, Ramon Brugada. _Front Cardiovasc Med._2018;5:149

Diagnosis and management of short QT syndrome (Contemp. Review) Preben Bjerregaard Heart Rhythm 2018;15:1261-1267

Differences in Short QT Syndrome Subtypes: A Systematic Literature Review and Pooled Analysis Laura S. Raschwitz, Ibrahim El-Battrawy, Kim Schlentrich, Johanne Besler, Michael Veith, Gretje Rotenberg, Volker Liebe, Rainer Schimpf, Siegfried Lang, Christian Wolpert, Xiaobo Zhou, Ibrahim Akin, Martin Borggrefe. Front Genet. 2019;10:1312

Short QT Syndrome: The current evidence of diagnosis and management. Ivana P, Dewi, Budi B. Dharmadjati. _J Arrhythm._2020; 36(6):962-966)

Inherited cardiac arrhythmias Peter J. Schwartz, Michael J, Ackerman, Charles Antzelevitch, Connie R. Bezzina, Martin Borggrefe, Bettina F. Cuneo, Arthur A.M. Wilde Nat Rev Dis Primers 2021;6(1):58. doi:10.1038/s41572-020-0188-7